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    2021 papers

    1.        Ji, T.;  Li, Y.;  Deng, X.;  Rwei, A. Y.;  Offen, A.;  Hall, S.;  Zhang, W.;  Zhao, C.;  Mehta, M.; Kohane, D. S., Delivery of local anaesthetics by a self-assembled supramolecular system mimicking their interactions with a sodium channel. Nature Biomedical Engineering 2021, 5 (9), 1099-1109.

    2.        Cheng, K.;  Zhao, R.;  Li, Y.;  Qi, Y.;  Wang, Y.;  Zhang, Y.;  Qin, H.;  Qin, Y.;  Chen, L.;  Li, C.;  Liang, J.;  Li, Y.;  Xu, J.;  Han, X.;  Anderson, G. J.;  Shi, J.;  Ren, L.;  Zhao, X.; Nie, G., Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology. Nature Communications 2021, 12 (1), 2041.

    3.        Wang, H.;  Liang, Y.;  Yin, Y.;  Zhang, J.;  Su, W.;  White, A. M.;  Jiang, B.;  Xu, J.;  Zhang, Y.;  Stewart, S.;  Lu, X.; He, X., Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug resistance. Nature Communications 2021, 12 (1), 312.

    4.        Wang, Y.;  Gong, N.;  Ma, C.;  Zhang, Y.;  Tan, H.;  Qing, G.;  Zhang, J.;  Wang, Y.;  Wang, J.;  Chen, S.;  Li, X.;  Ni, Q.;  Yuan, Y.;  Gan, Y.;  Chen, J.;  Li, F.;  Zhang, J.;  Ou, C.;  Zhao, Y.;  Liu, X.; Liang, X.-J., An amphiphilic dendrimer as a light-activable immunological adjuvant for in situ cancer vaccination. Nature Communications 2021, 12 (1), 4964.

    5.        Yang, P.-P.;  Li, Y.-J.;  Cao, Y.;  Zhang, L.;  Wang, J.-Q.;  Lai, Z.;  Zhang, K.;  Shorty, D.;  Xiao, W.;  Cao, H.;  Wang, L.;  Wang, H.;  Liu, R.; Lam, K. S., Rapid discovery of self-assembling peptides with one-bead one-compound peptide library. Nature Communications 2021, 12 (1), 4494.

    6.        Liu, Q.;  Wan, K.;  Shang, Y.;  Wang, Z.-G.;  Zhang, Y.;  Dai, L.;  Wang, C.;  Wang, H.;  Shi, X.;  Liu, D.; Ding, B., Cofactor-free oxidase-mimetic nanomaterials from self-assembled histidine-rich peptides. Nature Materials 2021, 20 (3), 395-402.

    7.        Cao, M.;  Cai, R.;  Zhao, L.;  Guo, M.;  Wang, L.;  Wang, Y.;  Zhang, L.;  Wang, X.;  Yao, H.;  Xie, C.;  Cong, Y.;  Guan, Y.;  Tao, X.;  Wang, Y.;  Xu, S.;  Liu, Y.;  Zhao, Y.; Chen, C., Molybdenum derived from nanomaterials incorporates into molybdenum enzymes and affects their activities in vivo. Nature Nanotechnology 2021, 16 (6), 708-716.

    8.        Zhang, Y.;  Han, X.; Nie, G., Responsive and activable nanomedicines for remodeling the tumor microenvironment. Nature Protocols 2021, 16 (1), 405-430.

    9.        Wang, J.;  Li, Y.; Nie, G., Multifunctional biomolecule nanostructures for cancer therapy. Nature Reviews Materials 2021, 6 (9), 766-783.

    10.    Bao, L.;  Cui, X.;  Wang, X.;  Wu, J.;  Guo, M.;  Yan, N.; Chen, C., Carbon Nanotubes Promote the Development of Intestinal Organoids through Regulating Extracellular Matrix Viscoelasticity and Intracellular Energy Metabolism. ACS nano 2021,

    11.    Fan, Y.;  Liu, S.;  Yi, Y.;  Rong, H.; Zhang, J., Catalytic Nanomaterials toward Atomic Levels for Biomedical Applications: From Metal Clusters to Single-Atom Catalysts. Acs Nano 2021, 15 (2), 2005-2037.

    12.    He, Y.;  Li, Z.;  Cong, C.;  Ye, F.;  Yang, J.;  Zhang, X.;  Yuan, Y.;  Ma, Z.;  Zhang, K.;  Lin, Y.;  Zheng, L.;  Liang, X.-J.; Gao, D., Pyroelectric Catalysis-Based "Nano-Lymphatic" Reduces Tumor Interstitial Pressure for Enhanced Penetration and Hydrodynamic Therapy. Acs Nano 2021, 15 (6), 10488-10501.

    13.    Liu, X.;  Zhang, W.;  Zheng, W.; Jiang, X., Micropatterned Coculture Platform for Screening Nerve-Related Anticancer Drugs. Acs Nano 2021, 15 (1), 637-649.

    14.    Wang, D.;  Wang, H.;  Ji, L.;  Xu, M.;  Bai, B.;  Wan, X.;  Hou, D.;  Qiao, Z.-Y.;  Wang, H.; Zhang, J., Hybrid Plasmonic Nanodumbbells Engineering for Multi-Intensified Second Near-Infrared Light Induced Photodynamic Therapy. Acs Nano 2021, 15 (5), 8694-8705.

    15.    Wang, J.;  Tian, X.;  Zhang, J.;  Tan, L.;  Ouyang, N.;  Jia, B.;  Chen, C.;  Ge, C.; Li, J., Postchronic Single-Walled Carbon Nanotube Exposure Causes Irreversible Malignant Transformation of Human Bronchial Epithelial Cells through DNA Methylation Changes. Acs Nano 2021, 15 (4), 7094-7104.

    16.    Yin, Y.;  Su, W.;  Zhang, J.;  Huang, W.;  Li, X.;  Ma, H.;  Tan, M.;  Song, H.;  Cao, G.;  Yu, S.;  Yu, D.;  Jeong, J. H.;  Zhao, X.;  Li, H.;  Nie, G.; Wang, H., Separable Microneedle Patch to Protect and Deliver DNA Nanovaccines Against COVID-19. Acs Nano 2021, 15 (9), 14347-14359.

    17.    Yue, Y.;  Li, F.;  Li, Y.;  Wang, Y.;  Guo, X.;  Cheng, Z.;  Li, N.;  Ma, X.;  Nie, G.; Zhao, X., Biomimetic Nanoparticles Carrying a Repolarization Agent of Tumor-Associated Macrophages for Remodeling of the Inflammatory Microenvironment Following Photothermal Therapy. Acs Nano 2021, 15 (9), 15166-15179.

    18.    Zhang, K.;  Zhang, H.;  Gao, Y.-H.;  Wang, J.-Q.;  Li, Y.;  Cao, H.;  Hu, Y.; Wang, L., A Monotargeting Peptidic Network Antibody Inhibits More Receptors for Anti-Angiogenesis. Acs Nano 2021, 15 (8), 13065-13076.

    19.    Zhang, L.;  Wu, Y.;  Yin, X.;  Zhu, Z.;  Rojalin, T.;  Xiao, W.;  Zhang, D.;  Huang, Y.;  Li, L.;  Baehr, C. M.;  Yu, X.;  Ajena, Y.;  Li, Y.;  Wang, L.; Lam, K. S., Tumor Receptor-Mediated In Vivo Modulation of the Morphology, Phototherapeutic Properties, and Pharmacokinetics of Smart Nanomaterials. Acs Nano 2021, 15 (1), 468-479.

    20.    Zhao, X.;  Yang, X.;  Wang, X.;  Zhao, X.;  Zhang, Y.;  Liu, S.;  Anderson, G. J.;  Kim, S.-j.;  Li, Y.; Nie, G., Penetration Cascade of Size Switchable Nanosystem in Desmoplastic Stroma for Improved Pancreatic Cancer Therapy. Acs Nano 2021, 15 (9), 14149-14161.

    21.    Zhao, Y.;  Zhao, T.;  Cao, Y.;  Sun, J.;  Zhou, Q.;  Chen, H.;  Guo, S.;  Wang, Y.;  Zhen, Y.;  Liang, X.-J.; Zhang, S., Temperature-Sensitive Lipid-Coated Carbon Nanotubes for Synergistic Photothermal Therapy and Gene Therapy. Acs Nano 2021, 15 (4), 6517-6529.

    22.    Zheng, P.;  Fan, M.;  Liu, H.;  Zhang, Y.;  Dai, X.;  Li, H.;  Zhou, X.;  Hu, S.;  Yang, X.;  Jin, Y.;  Yu, N.;  Guo, S.;  Zhang, J.;  Liang, X.-J.;  Cheng, K.; Li, Z., Self-Propelled and Near-Infrared-Phototaxic Photosynthetic Bacteria as Photothermal Agents for Hypoxia-Targeted Cancer Therapy. Acs Nano 2021, 15 (1), 1100-1110.

    23.    Zhou, Q.;  Gong, N.;  Zhang, D.;  Li, J.;  Han, X.;  Dou, J.;  Huang, J.;  Zhu, K.;  Liang, P.;  Liang, X.-J.; Yu, J., Mannose-Derived Carbon Dots Amplify Microwave Ablation-Induced Antitumor Immune Responses by Capturing and Transferring "Danger Signals" to Dendritic Cells. Acs Nano 2021, 15 (2), 2920-2932.

    24.    Li, J.;  Kong, J.;  Ma, S.;  Li, J.;  Mao, M.;  Chen, K.;  Chen, Z.;  Zhang, J.;  Chang, Y.;  Yuan, H.;  Liu, T.;  Zhang, Z.; Xing, G., Exosome-Coated B-10 Carbon Dots for Precise Boron Neutron Capture Therapy in a Mouse Model of Glioma In Situ. Advanced Functional Materials 2021, 31 (24), 2100969.

    25.    Liu, X.;  Xie, X.;  Jiang, J.;  Lin, M.;  Zheng, E.;  Qiu, W.;  Yeung, I.;  Zhu, M.;  Li, Q.;  Xia, T.; Meng, H., Use of Nanoformulation to Target Macrophages for Disease Treatment. Advanced Functional Materials 2021, 31 (38), 2104487.

    26.    Li, S.;  Xu, S.;  Liang, X.;  Xue, Y.;  Mei, J.;  Ma, Y.;  Liu, Y.; Liu, Y., Nanotechnology: Breaking the Current Treatment Limits of Lung Cancer. Advanced Healthcare Materials 2021, 10 (12), 2100078.

    27.    Taleb, M.;  Atabakhshi-Kashi, M.;  Wang, Y.;  Rezavani Alanagh, H.;  Farhadi Sabet, Z.;  Li, F.;  Cheng, K.;  Li, C.;  Qi, Y.;  Nie, G.; Ying, Z., Bifunctional Therapeutic Peptide Assembled Nanoparticles Exerting Improved Activities of Tumor Vessel Normalization and Immune Checkpoint Inhibition. Advanced Healthcare Materials 2021, 10 (12), 2100051.

    28.    Wang, G.-Q.;  Yang, J.;  Hou, D.-Y.;  Zheng, R.;  Mamuti, M.;  Guo, M.-J.;  Fan, Z.;  An, H.-W.; Wang, H., Conformational Transition-Triggered Disassembly of Therapeutic Peptide Nanomedicine for Tumor Therapy. Advanced Healthcare Materials 2021, 2100333.

    29.    Wang, Y.;  Xia, B.;  Huang, Q.;  Luo, T.;  Zhang, Y.;  Timashev, P.;  Guo, W.;  Li, F.; Liang, X.-J., Practicable Applications of Aggregation-Induced Emission with Biomedical Perspective. Advanced Healthcare Materials 2021, 2100945.

    30.    Xie, J.;  Zhao, M.;  Wang, C.;  Yong, Y.;  Gu, Z.; Zhao, Y., Rational Design of Nanomaterials for Various Radiation-Induced Diseases Prevention and Treatment. Advanced Healthcare Materials 2021, 10 (6), 2001615.

    31.    Xu, Q.;  Hua, Y.;  Zhang, Y.;  Lv, M.;  Wang, H.;  Pi, Y.;  Xie, J.;  Wang, C.; Yong, Y., A Biofilm Microenvironment-Activated Single-Atom Iron Nanozyme with NIR-Controllable Nanocatalytic Activities for Synergetic Bacteria-Infected Wound Therapy. Advanced healthcare materials 2021, e2101374-e2101374.

    32.    Zhang, C.;  Xie, Q.;  Cha, R.;  Ding, L.;  Jia, L.;  Mou, L.;  Cheng, S.;  Wang, N.;  Li, Z.;  Sun, Y.;  Cui, C.;  Zhang, Y.;  Zhang, Y.;  Zhou, F.; Jiang, X., Anticoagulant Hydrogel Tubes with Poly(epsilon-Caprolactone) Sheaths for Small-Diameter Vascular Grafts. Advanced Healthcare Materials 2021, 10 (19), 2100839.

    33.    Zhou, H.;  Qin, F.; Chen, C., Designing Hypoxia-Responsive Nanotheranostic Agents for Tumor Imaging and Therapy. Advanced Healthcare Materials 2021, 10 (5), 2001277.

    34.    Zhu, S.;  Liu, Y.;  Gu, Z.; Zhao, Y., A Bibliometric Analysis of Advanced Healthcare Materials: Research Trends of Biomaterials in Healthcare Application. Advanced Healthcare Materials 2021, 10 (10), 2002222.

    35.    Cheng, H.-B.;  Zhang, S.;  Qi, J.;  Liang, X.-J.; Yoon, J., Advances in Application of Azobenzene as a Trigger in Biomedicine: Molecular Design and Spontaneous Assembly. Advanced Materials 2021, 33 (26), 2007290.

    36.    Qin, H.;  Zhao, R.;  Qin, Y.;  Zhu, J.;  Chen, L.;  Di, C.;  Han, X.;  Cheng, K.;  Zhang, Y.;  Zhao, Y.;  Shi, J.;  Anderson, G. J.;  Zhao, Y.; Nie, G., Development of a Cancer Vaccine Using In Vivo Click-Chemistry-Mediated Active Lymph Node Accumulation for Improved Immunotherapy. Advanced Materials 2021, 33 (20), 2006007.

    37.    Qiu, N.;  Wang, G.;  Wang, J.;  Zhou, Q.;  Guo, M.;  Wang, Y.;  Hu, X.;  Zhou, H.;  Bai, R.;  You, M.;  Zhang, Z.;  Chen, C.;  Liu, Y.; Shen, Y., Tumor-Associated Macrophage and Tumor-Cell Dually Transfecting Polyplexes for Efficient Interleukin-12 Cancer Gene Therapy. Advanced Materials 2021, 33 (2), 2006189.

    38.    Wu, J.;  Wang, Z.;  Jin, X.;  Zhang, S.;  Li, T.;  Zhang, Y.;  Xing, H.;  Yu, Y.;  Zhang, H.;  Gao, X.; Wei, H., Hammett Relationship in Oxidase-Mimicking Metal-Organic Frameworks Revealed through a Protein-Engineering-Inspired Strategy. Advanced Materials 2021, 33 (3), 2005024.

    39.    Zhou, X.;  You, M.;  Wang, F.;  Wang, Z.;  Gao, X.;  Jing, C.;  Liu, J.;  Guo, M.;  Li, J.;  Luo, A.;  Liu, H.;  Liu, Z.; Chen, C., Multifunctional Graphdiyne-Cerium Oxide Nanozymes Facilitate MicroRNA Delivery and Attenuate Tumor Hypoxia for Highly Efficient Radiotherapy of Esophageal Cancer. Advanced Materials 2021, 33 (24), 2100556.

    40.    Chang, T.;  Moses, O. A.;  Tian, C.;  Wang, H.;  Song, L.; Zhao, G., Synergistic Ice Inhibition Effect Enhances Rapid Freezing Cryopreservation with Low Concentration of Cryoprotectants. Advanced Science 2021, 8 (6), 2003387.

    41.    Hu, X.;  Xia, F.;  Lee, J.;  Li, F.;  Lu, X.;  Zhuo, X.;  Nie, G.; Ling, D., Tailor-Made Nanomaterials for Diagnosis and Therapy of Pancreatic Ductal Adenocarcinoma. Advanced Science 2021, 8 (7), 2002545.

    42.    Liu, H.;  Liu, Y.;  Mehdi, S.;  Wu, X.;  Liu, T.;  Zhou, B.;  Zhang, P.;  Jiang, J.; Li, B., Surface Phosphorus-Induced CoO Coupling to Monolithic Carbon for Efficient Air Electrode of Quasi-Solid-State Zn-Air Batteries. Advanced Science 2021, 2101314.

    43.    Liu, X.;  Zhang, Y.;  Guo, Y.;  Jiao, W.;  Gao, X.;  Lee, W. S. V.;  Wang, Y.;  Deng, X.;  He, Y.;  Jiao, J.;  Zhang, C.;  Hu, G.;  Liang, X.-J.; Fan, H., Electromagnetic Field-Programmed Magnetic Vortex Nanodelivery System for Efficacious Cancer Therapy. Advanced Science 2021, 8 (18), 2100950.

    44.    Ye, S.;  Li, W.;  Wang, H.;  Zhu, L.;  Wang, C.; Yang, Y., Quantitative Nanomechanical Analysis of Small Extracellular Vesicles for Tumor Malignancy Indication. Advanced Science 2021, 8 (18), 2100825.

    45.    Zhang, C.;  Wang, X.;  Du, J.;  Gu, Z.; Zhao, Y., Reactive Oxygen Species-Regulating Strategies Based on Nanomaterials for Disease Treatment. Advanced Science 2021, 8 (3), 2002797.

    46.    Zhang, F.;  Hou, Y.;  Zhu, M.;  Deng, B.;  Zhao, M.;  Zhu, X.;  Sun, Y.;  Chen, D.;  Jiang, C.;  Wang, L.;  Chen, C.;  Chen, H.;  Chen, H.;  Zheng, H.; Li, W., Death Pathways of Cancer Cells Modulated by Surface Molecule Density on Gold Nanorods. Advanced Science 2021, 2102666.

    47.    Chen, M.;  Lin, Z.;  Xuan, M.;  Lin, X.;  Yang, M.;  Dai, L.; He, Q., Programmable Dynamic Shapes with a Swarm of Light-Powered Colloidal Motors. Angewandte Chemie-International Edition 2021, 60 (30), 16674-16679.

    48.    Fan, Z.;  Zhao, J.;  Chai, X.; Li, L., A Cooperatively Activatable, DNA-based Fluorescent Reporter for Imaging of Correlated Enzymatic Activities. Angewandte Chemie-International Edition 2021, 60 (27), 14887-14891.

    49.    Liu, C.;  Chen, Y.;  Zhao, J.;  Wang, Y.;  Shao, Y.;  Gu, Z.;  Li, L.; Zhao, Y., Self-Assembly of Copper-DNAzyme Nanohybrids for Dual-Catalytic Tumor Therapy. Angewandte Chemie-International Edition 2021, 60 (26), 14324-14328.

    50.    Liu, J.;  Wang, A.;  Liu, S.;  Yang, R.;  Wang, L.;  Gao, F.;  Zhou, H.;  Yu, X.;  Liu, J.; Chen, C., A Titanium Nitride Nanozyme for pH-Responsive and Irradiation-Enhanced Cascade-Catalytic Tumor Therapy. Angewandte Chemie-International Edition 2021, 60, 2-12.

    51.    Liu, X.;  Jia, Y.;  Han, Z.;  Hou, Q.;  Zhang, W.;  Zheng, W.; Jiang, X., Integrating a Concentration Gradient Generator and a Single-Cell Trapper Array for High-Throughput Screening the Bioeffects of Nanomaterials. Angewandte Chemie-International Edition 2021, 60 (22), 12319-12322.

    52.    Liu, Z.;  Wang, X.;  Chen, Q.;  Ma, F.;  Huang, Y.;  Gao, Y.;  Deng, Q.;  Qiao, Z.-Y.;  Xing, X.;  Zhu, J.;  Lu, F.; Wang, H., Regulating Twisted Skeleton to Construct Organ-Specific Perylene for Intensive Cancer Chemotherapy. Angewandte Chemie-International Edition 2021, 60 (29), 16215-16223.

    53.    Shao, Y.;  Zhao, J.;  Yuan, J.;  Zhao, Y.; Li, L., Organelle-Specific Photoactivation of DNA Nanosensors for Precise Profiling of Subcellular Enzymatic Activity. Angewandte Chemie-International Edition 2021, 60 (16), 8923-8931.

    54.    Xiang, Z.;  Zhao, J.;  Yi, D.;  Di, Z.; Li, L., Peptide Nucleic Acid (PNA)-Guided Peptide Engineering of an Aptamer Sensor for Protease-Triggered Molecular Imaging. Angewandte Chemie-International Edition 2021, 60, 22659 –22663.

    55.    Yi, D.;  Zhao, J.; Li, L., An Enzyme-Activatable Engineered DNAzyme Sensor for Cell-Selective Imaging of Metal Ions. Angewandte Chemie-International Edition 2021, 60 (12), 6300-6304.

    56.    Zhao, J.;  Li, Z.;  Shao, Y.;  Hu, W.; Li, L., Spatially Selective Imaging of Mitochondrial MicroRNAs via Optically Programmable Strand Displacement Reactions. Angewandte Chemie-International Edition 2021, 60 (33), 17937-17941.

    57.    Zheng, R.;  Yang, J.;  Mamuti, M.;  Hou, D.-Y.;  An, H.-W.;  Zhao, Y.; Wang, H., Controllable Self-Assembly of Peptide-Cyanine Conjugates In Vivo as Fine-Tunable Theranostics. Angewandte Chemie-International Edition 2021, 60 (14), 7809-7819.

    58.    Ali, A.;  Ovais, M.;  Zhou, H.;  Rui, Y.; Chen, C., Tailoring metal-organic frameworks-based nanozymes for bacterial theranostics. Biomaterials 2021, 275, 120951.

    59.    Baehr, C. M.;  Zhang, L.;  Wu, Y.;  Domokos, A.;  Xiao, W.;  Wang, L.; Lam, K. S., Transformable amyloid-beta mimetic peptide amphiphiles for lysosomal disruption in non-small cell lung cancer. Biomaterials 2021, 277, 121078-121078.

    60.    Du, C.;  Zhou, M.;  Jia, F.;  Ruan, L.;  Lu, H.;  Zhang, J.;  Zhu, B.;  Liu, X.;  Chen, J.;  Chai, Z.; Hu, Y., D-arginine-loaded metal-organic frameworks nanoparticles sensitize osteosarcoma to radiotherapy. Biomaterials 2021, 269, 120642.

    61.    Wang, D.;  Cheng, D.-B.;  Ji, L.;  Niu, L.-J.;  Zhang, X.-H.;  Cong, Y.;  Cao, R.-H.;  Zhou, L.;  Bai, F.;  Qiao, Z.-Y.; Wang, H., Precise magnetic resonance imaging-guided sonodynamic therapy for drug-resistant bacterial deep infection. Biomaterials 2021, 264, 120386.

    62.    Wang, D.;  Xue, M.;  Chen, J.;  Chen, H.;  Liu, J.;  Li, Q.;  Xie, Y.;  Hu, Y.;  Ni, Y.; Zhou, Q., Macrophage-derived implantable vaccine prevents postsurgical tumor recurrence. Biomaterials 2021, 278, 121161-121161.

    63.    Wang, H.;  Jin, Y.;  Tan, Y.;  Zhu, H.;  Huo, W.;  Niu, P.;  Li, Z.;  Zhang, J.;  Liang, X.-j.; Yang, X., Photo-responsive hydrogel facilitates nutrition deprivation by an ambidextrous approach for preventing cancer recurrence and metastasis. Biomaterials 2021, 275, 120992.

    64.    Wang, M.-D.;  Hou, D.-Y.;  Lv, G.-T.;  Li, R.-X.;  Hu, X.-J.;  Wang, Z.-J.;  Zhang, N.-Y.;  Yi, L.;  Xu, W.-H.; Wang, H., Targeted in situ self-assembly augments peptide drug conjugate cell-entry efficiency. Biomaterials 2021, 278, 121139-121139.

    65.    Wu, X.;  Yang, H.;  Chen, X.;  Gao, J.;  Duan, Y.;  Wei, D.;  Zhang, J.;  Ge, K.;  Liang, X.-J.;  Huang, Y.;  Feng, S.;  Zhang, R.;  Chen, X.; Chang, J., Nano-herb medicine and PDT induced synergistic immunotherapy for colon cancer treatment. Biomaterials 2021, 269, 120654.

    66.    Yang, Y.;  Liu, X.;  Ma, W.;  Xu, Q.;  Chen, G.;  Wang, Y.;  Xiao, H.;  Li, N.;  Liang, X.-J.;  Yu, M.; Yu, Z., Light-activatable liposomes for repetitive on-demand drug release and immunopotentiation in hypoxic tumor therapy. Biomaterials 2021, 265, 120456.

    67.    Yao, Q.;  Gao, S.;  Wu, C.;  Lin, T.; Gao, Y., Enzymatic non-covalent synthesis of supramolecular assemblies as a general platform for bioorthogonal prodrugs activation to combat drug resistance. Biomaterials 2021, 277, 121119.

    68.    Zhang, C.;  Wang, X.;  Dong, X.;  Mei, L.;  Wu, X.;  Gu, Z.; Zhao, Y., X-ray-facilitated redox cycling of nanozyme possessing peroxidase-mimicking activity for reactive oxygen species-enhanced cancer therapy. Biomaterials 2021, 276, 121023.

    69.    Zhang, K.;  Zhang, H.;  Zou, X.-R.;  Hu, Y.;  Hou, D.-Y.;  Fan, J.-Q.;  Yang, C.;  Chen, Z.-M.;  Wen, S.-F.;  Cao, H.;  Yang, P.-P.; Wang, L., An antibody-like peptidic network for anti-angiogenesis. Biomaterials 2021, 275, 120900.

    70.    Zhang, T.;  Li, G.;  Miao, Y.;  Lu, J.;  Gong, N.;  Zhang, Y.;  Sun, Y.;  He, Y.;  Peng, M.;  Liu, X.;  Liang, X.-J.; Fan, H., Magnetothermal regulation of in vivo protein corona formation on magnetic nanoparticles for improved cancer nanotherapy. Biomaterials 2021, 276, 121021.

    71.    Zhao, Y.-D.;  Muhetaerjiang, M.;  An, H.-W.;  Fang, X.;  Zhao, Y.; Wang, H., Nanomedicine enables spatiotemporally regulating macrophage-based cancer immunotherapy. Biomaterials 2021, 268, 120552.

    72.    Zhong, J.;  Xia, B.;  Shan, S.;  Zheng, A.;  Zhang, S.;  Chen, J.; Liang, X.-J., High-quality milk exosomes as oral drug delivery system. Biomaterials 2021, 277, 121126.

    73.    Geng, H.;  Zhou, M.;  Li, B.;  Liu, L.;  Yang, X.;  Wen, Y.;  Yu, H.;  Wang, H.;  Chen, J.; Chen, L., Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma. Chemical Engineering Journal 2021, 417, 128103.

    74.    Li, X.;  Pan, Z. a.;  Xiang, C.;  Yuan, Y.;  Chen, J.;  Qing, G.;  Ma, J.;  Liang, X.-J.;  Wu, Y.; Guo, W., Structure transformable nanoparticles for photoacoustic imaging-guided photothermal ablation of tumors via enzyme-induced multistage delivery. Chemical Engineering Journal 2021, 421, 127747.

    75.    Mei, L.;  Zhu, S.;  Liu, Y.;  Yin, W.;  Gu, Z.; Zhao, Y., An overview of the use of nanozymes in antibacterial applications. Chemical Engineering Journal 2021, 418, 129431.

    76.    Fan, J.-Q.;  Li, Y.-J.;  Wei, Z.-J.;  Fan, Y.;  Li, X.-D.;  Chen, Z.-M.;  Hou, D.-Y.;  Xiao, W.-Y.;  Ding, M.-R.;  Wang, H.; Wang, L., Binding-Induced Fibrillogenesis Peptides Recognize and Block Intracellular Vimentin Skeletonization against Breast Cancer. Nano Letters 2021, 21 (14), 6202-6210.

    77.    Guo, M.;  Zhao, L.;  Liu, J.;  Wang, X.;  Yao, H.;  Chang, X.;  Liu, Y.;  Liu, J.;  You, M.;  Ren, J.;  Wang, F.;  Wang, L.;  Wang, Y.;  Liu, H.;  Li, Y.;  Zhao, Y.;  Cai, R.; Chen, C., The Underlying Function and Structural Organization of the Intracellular Protein Corona on Graphdiyne Oxide Nanosheet for Local Immunomodulation. Nano Letters 2021, 21 (14), 6005-6013.

    78.    Li, B.;  Chu, T.;  Wei, J.;  Zhang, Y.;  Qi, F.;  Lu, Z.;  Gao, C.;  Zhang, T.;  Jiang, E.;  Xu, J.;  Xu, J.;  Li, S.; Nie, G., Platelet-Membrane-Coated Nanoparticles Enable Vascular Disrupting Agent Combining Anti-Angiogenic Drug for Improved Tumor Vessel Impairment. Nano Letters 2021, 21 (6), 2588-2595.

    79.    Li, C.;  Zhou, J.;  Wu, Y.;  Dong, Y.;  Du, L.;  Yang, T.;  Wang, Y.;  Guo, S.;  Zhang, M.;  Hussain, A.;  Xiao, H.;  Weng, Y.;  Huang, Y.;  Wang, X.;  Liang, Z.;  Cao, H.;  Zhao, Y.;  Liang, X.-J.;  Dong, A.; Huang, Y., Core Role of Hydrophobic Core of Polymeric Nanomicelle in Endosomal Escape of siRNA. Nano Letters 2021, 21 (8), 3680-3689.

    80.    Liu, D.;  Deng, B.;  Liu, Z.;  Ma, B.;  Leng, X.;  Kong, D.;  Ji, T.; Liu, L., Enhanced Antitumor Immune Responses via a Self-Assembled Carrier-Free Nanovaccine. Nano Letters 2021, 21 (9), 3965-3973.

    81.    Wang, L.;  Yang, J.;  Li, S.;  Li, Q.;  Liu, S.;  Zheng, W.; Jiang, X., Oral Administration of Starting Materials for In Vivo Synthesis of Antibacterial Gold Nanoparticles for Curing Remote Infections. Nano Letters 2021, 21 (2), 1124-1131.

    82.    Yin, Y.;  Li, X.;  Ma, H.;  Zhang, J.;  Yu, D.;  Zhao, R.;  Yu, S.;  Nie, G.; Wang, H., In Situ Transforming RNA Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy. Nano Letters 2021, 21 (5), 2224-2231.

    83.    Zhang, H.;  Cao, Y.;  Xu, D.;  Goh, N. S.;  Demirer, G. S.;  Cestellos-Blanco, S.;  Chen, Y.;  Landry, M. P.; Yang, P., Gold-Nanocluster-Mediated Delivery of siRNA to Intact Plant Cells for Efficient Gene Knockdown. Nano Letters 2021, 21 (13), 5859-5866.

    84.    Zhang, J.;  Di, Z.;  Yan, H.;  Zhao, Y.; Li, L., One-Step Synthesis of Single-Stranded DNA-Bridged Iron Oxide Supraparticles as MRI Contrast Agents. Nano Letters 2021, 21 (7), 2793-2799.

    85.    Bondarenko, O.;  Mortimer, M.;  Kahru, A.;  Feliu, N.;  Javed, I.;  Kakinen, A.;  Lin, S.;  Xia, T.;  Song, Y.;  Davis, T. P.;  Lynch, I.;  Parak, W. J.;  Leong, D. T.;  Ke, P. C.;  Chen, C.; Zhao, Y., Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decade. Nano Today 2021, 39, 101184.

    86.    Cai, X.;  Xu, Y.;  Zhao, L.;  Xu, J.;  Li, S.;  Wen, C.;  Xia, X.;  Dong, Q.;  Hu, X.;  Wang, X.;  Chen, L.;  Chen, Z.; Tan, W., In situ pepsin-assisted needle assembly of magnetic-graphitic-nanocapsules for enhanced gastric retention and mucus penetration. Nano Today 2021, 36, 101032.

    87.    Chen, K.;  Wang, Y.;  Liang, H.;  Huang, H.;  Liang, Y.;  Zhang, J.;  Chang, Y.-n.;  Li, J.;  Fang, M.; Xing, G., Fullerenols boosting the therapeutic effect of anti-CD47 antibody to trigger robust anti-tumor immunity by inducing calreticulin exposure. Nano Today 2021, 37, 101070.

    88.    Gao, J.;  Zeng, L.;  Yao, L.;  Wang, Z.;  Yang, X.;  Shi, J.;  Hu, L.;  Liu, Q.;  Chen, C.;  Xia, T.;  Qu, G.;  Zhang, X.-E.; Jiang, G., Inherited and acquired corona of coronavirus in the host: Inspiration from the biomolecular corona of nanoparticles. Nano Today 2021, 39, 101161.

    89.    Guo, J.-C.;  An, Q.;  Guo, M.;  Xiao, Y.;  Li, B.;  Gao, F.;  Wang, Y.;  Li, J.;  Wang, Y.;  Liu, Y.;  Meng, H.;  Guo, J.; Liu, J., Oxygen-independent free radical generation mediated by core-shell magnetic nanocomposites synergizes with immune checkpoint blockade for effective primary and metastatic tumor treatment. Nano Today 2021, 36, 101024.

    90.    He, L.;  Zhao, J.;  Wang, L.;  Liu, Q.;  Fan, Y.;  Li, B.;  Yu, Y.-L.;  Chen, C.; Li, Y.-F., Using nano -selenium to combat Coronavirus Disease 2019 (COVID-19)? Nano Today 2021, 36, 101037.

    91.    Lin, X.;  Wang, L.;  Zhao, J.;  He, L.;  Cui, L.;  Gao, Y.;  Chen, C.;  Fan, Y.;  Li, B.; Li, Y.-F., Nanosafety evaluation through feces: A comparison between selenium nanoparticles and selenite in rats. Nano Today 2021, 36, 101010.

    92.    Mamuti, M.;  Zheng, R.;  An, H.-W.; Wang, H., In vivo self-assembled nanomedicine. Nano Today 2021, 36, 101036.

    93.    Qin, Y.;  Zhao, R.;  Qin, H.;  Chen, L.;  Chen, H.;  Zhao, Y.; Nie, G., Colonic mucus-accumulating tungsten oxide nanoparticles improve the colitis therapy by targeting Enterobacteriaceae. Nano Today 2021, 39, 101234.

    94.    Sun, H.;  Zhang, Q.;  Li, J.;  Peng, S.;  Wang, X.; Cai, R., Near-infrared photoactivated nanomedicines for photothermal synergistic cancer therapy. Nano Today 2021, 37, 101073.

    95.    Wang, C.;  Di, Z.;  Xiang, Z.;  Zhao, J.; Li, L., Coordination-driven assembly of proteins and nucleic acids in a single architecture for carrier-free intracellular co-delivery. Nano Today 2021, 38, 101140.

    96.    Wang, M.;  Li, S.;  Chen, Z.;  Zhu, J.;  Hao, W.;  Jia, G.;  Chen, W.;  Zheng, Y.;  Qu, W.; Liu, Y., Safety assessment of nanoparticles in food: Current status and prospective. Nano Today 2021, 39, 101169.

    97.    Wang, X.;  Zhang, D.;  Jiang, N.;  Wang, X.;  Zhang, N.;  Zhang, K.;  Sang, X.;  Feng, Y.;  Chen, R.;  Yang, N.; Chen, Q., Induction of apoptosis in Trypanosoma brucei following endocytosis of ultra-small noble metal nanoclusters. Nano Today 2021, 38, 101122.

    98.    Wang, Y.;  Xie, Y.;  Luo, J.;  Guo, M.;  Hu, X.;  Chen, X.;  Chen, Z.;  Lu, X.;  Mao, L.;  Zhang, K.;  Wei, L.;  Ma, Y.;  Wang, R.;  Zhou, J.;  He, C.;  Zhang, Y.;  Zhang, Y.;  Chen, S.;  Shen, L.;  Chen, Y.;  Qiu, N.;  Liu, Y.;  Cui, Y.;  Liao, G.;  Liu, Y.; Chen, C., Engineering a self-navigated MnARK nanovaccine for inducing potent protective immunity against novel coronavirus. Nano Today 2021, 38, 101139.

    99.    Yang, T.;  Huang, D.;  Li, C.;  Zhao, D.;  Li, J.;  Zhang, M.;  Chen, Y.;  Wang, Q.;  Liang, Z.;  Liang, X.-J.;  Li, Z.; Huang, Y., Rolling microneedle electrode array (RoMEA) empowered nucleic acid delivery and cancer immunotherapy. Nano Today 2021, 36, 101017.

    100.Yao, H.;  Yao, H.;  Huang, H.;  Zhang, L.;  Cui, R.;  Guo, X.;  Cheng, H.;  Li, Y.;  Li, X.;  Gao, X.;  Zhao, L.; Sun, B., Carbon phase adjustment by multi-configuration ligand in endohedral metallofullerene derivatives Gd@C-82(morpholine)(7) under high pressure. Nano Today 2021, 37, 101079.

    101.Yu, H.;  Wang, B.;  Zhou, S.;  Zhu, M.;  Chen, W.;  Chen, H.;  Li, X.;  Liang, S.;  Wang, M.;  Zheng, L.;  Zhao, L.;  Chai, Z.; Feng, W., Polyvinylpyrrolidone functionalization induces deformable structure of graphene oxide nanosheets for lung-targeting delivery. Nano Today 2021, 38, 101151.

    102.Zhou, R.;  Yan, L.;  Dong, X.;  Zhu, S.;  Chen, K.;  Wu, Y.;  Xiang, H.;  Li, L.;  Zhang, G.;  Gu, Z.; Zhao, Y., Fractionated regimen-suitable immunoradiotherapy sensitizer based on ultrasmall Fe4Se2W18 nanoclusters enable tumor-specific radiosensitization augment and antitumor immunity boost. Nano Today 2021, 36, 101003.

    103.Zhu, S.;  Meng, H.;  Gu, Z.; Zhao, Y., Research trend of nanoscience and nanotechnology - A bibliometric analysis of Nano Today. Nano Today 2021, 39, 101233.

    104.Zhu, L.;  Liu, J.;  Zhou, G.;  Liu, T.-M.;  Dai, Y.;  Nie, G.; Zhao, Q., Remodeling of Tumor Microenvironment by Tumor-Targeting Nanozymes Enhances Immune Activation of CAR T Cells for Combination Therapy. Small 2021, 2102624.

    105.Zhao, M.;  Wang, C.;  Xie, J.;  Ji, C.; Gu, Z., Eco-Friendly and Scalable Synthesis of Fullerenols with High Free Radical Scavenging Ability for Skin Radioprotection. Small 2021, 17 (37), 2102035.

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    Chinese Academy of Sciences