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Lina Zhao


Lina Zhao, Associate Professor, PhD

Chinese Academy of Sciences Key Lab for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences (CAS)




Dr. Lina Zhao received her Bachelor’s Degree in Applied Physics (2000) and obtained her Ph.D. in Condensed Matter Physics (2005) from Beijing Institute of Technology. From 2005 to 2007, she worked as a postdoctoral researcher at State Key Laboratory for Artificial Microstructure and Mesoscopic Physics in Peking University. After her postdoctoral research, she joined Nanyang Technological University (NTU) of Singapore as a Research Scientist working in the joint project between NTU and Atomistix Pte. Ltd. for two and a half years. Her recent research interest is the mechanism of nano-bio effects with multi-scale theoretical methods including nanoparticle-protein interaction for cancer inhibition nanomedicine development, novel ligand based nanoprobe design for important protein targeting detection and nanotoxicity origin of nanomaterial in cell. She is also interested in using deep learning method to study the nano/bio interface effects mentioned above based on big data. Published >50 peer-review SCI scientific papers and one coauthored book in English, with citation by >3,000 times in international journals. She has directed 3 research projects from NSFC, and 1 subproject from MOST973. She is the deputy editor of J. Nanosci. Lett.. She won the ACS Nano Youth Scientist Award in 2016.


Research Interests

(1) Multi-scale theoretical simulations of the nano-biomedical effect molecular mechanism

(2) Deep learning algorithm and technique in nanomedicine design and development


Recent Publications

[1] Xudong Feng, Xiaoyan Wang, Beijia Han, Changling Zou, Yuhui Hou, Lina Zhao*, Chun Li*, “Design of Glyco-Linkers at Multiple Structural Levels to Modulate Protein Stability”, J. Phys. Chem. Lett., 9, 4638-4645, 2018. (IF: 9.353)

[2] Yanyan Cui, Yaling Wang*, Lina Zhao*, “Cysteine-Ag Cluster Hydrogel Confirmed by Experimental and Numerical Studies”, Small, 11, 5118-5125, 2015. (IF: 9.598)

[3] Qingming Deng, Lina Zhao*, Xingfa Gao, Meng Zhang, Youhua Luo, Yuliang Zhao*, “Single Layer of Polymeric Co-Phthalocyanine: Promising Low-Cost and High Activity Nanocatalysts for CO Oxidation”, Small, 9, 3506-3513, 2013. (IF: 9.598)

[4] Hui Wang, Xu Li, Liang Gao, Jiao Zhai, Ru Liu, Xueyun Gao, Dongqi Wang, Lina Zhao*, “Atomic structure of a peptide coated gold nanocluster identified using theoretical and experimental studies”, Nanoscale, 8, 11454-11460, 2016. (IF: 7.233)

[5] Lina Zhao, Jiao Zhai, Xuejie Zhang, Xueyun Gao*, Xiaohong Fang, Jingyuan Li*, “Computational design of peptide-Au cluster probe for sensitive detection of aIIbb3 integrin”, Nanoscale, 8, 4203-4208, 2016. (IF: 7.233)

[6] Xiaohui Yin, Lina Zhao(first co-author), Seung-gu Kang, Jun Pan, Yan Song, Mingyi Zhang, Gengmei Xing, Fei Wang, Jingyuan Li*, Ruhong Zhou*, Yuliang Zhao*, “Impacts of fullerene derivatives on regulating the structure and assembly of collagen molecules”, Nanoscale, 5, 7341-7348, 2013. (IF: 7.233)

[7] Qingming Deng, Lina Zhao*, Youhua Luo, Meng Zhang, Lixia Zhao, Yuliang Zhao*, “Carbon-Tuned Bonding Method Significantly Enhanced the Hydrogen Storage of BN–Li Complexes”, Nanoscale, 3, 4824-4829, 2011. (IF: 7.233)

[8] Qingming Deng, Lina Zhao*, Youhua Luo*, Meng Zhang, Long Jing, Yuliang Zhao*, “Ferromagnetism/ Antiferromagnetism Transition between Semihydrogenated and Fully-Aminated Single-Wall Carbon Nanotubes”, Nanoscale, 3, 3743-3746, 2011. (IF: 7.233)

[9] Shibo Xia, Juan Li, Mian Zu, Jinxia Li, Jinke Liu, Xue Bai, Yanan Chang, Kui Chen, Weihong Gu, Li Zeng, Lina Zhao*, Gengyan Xing*, Gengmei Xing*, “Small size fullerenol nanoparticles inhibit thrombosis and blood coagulation through inhibiting activities of thrombin and FXa”, Nanomedicine: NBM, 14, 929-939, 2018. (IF: 6.500)

[10] Junjiang Jin, Ying Dong, Ying Wang, Lin Xia, Weihong Gu, Xue Bai, Yanan Chang, Mingyi Zhang, Kui Chen, Juan Li*, Lina Zhao*, Gengmei Xing*, “Fullerenol Nanoparticles with Structural Activity Induce Variable Intracellular Actin Filament Morphologies”, J. Biomed. Nanotechnol., 12, 1234-1244, 2016. (IF: 5.068)

[11] Meiqing Liu, Liang Gao*, Lina Zhao*, Jian He, Qing Yuan, Peng Zhang, Yawei Zhao, Xueyun Gao*, “Peptide-Au Clusters Induced Tumor Cells Apoptosis via Targeting Glutathione Peroxidase-1: The Molecular Dynamics Assisted Experimental Studies”, Sci. Rep., 7, 131-140, 2017. (IF: 4.122)

[12] Peng Zhang, Jiao Zhai, Xueyun Gao, Hongkang Zhao, Wenyong Su, Lina Zhao*, “Targeted peptide-Au cluster binds to epidermal growth factor receptor (EGFR) in both active and inactive states: a clue for cancer inhibition through dual pathways”, Sci. Bull., 63, 349-355, 2018. (IF: 4.136 )

[13] Lina Zhao, Yuliang Zhao*, Ruhong Zhou*, “Novel Design of a Nanoflowmeter Based on Carbon Nanotubes”, J. Phys. Chem. C, 116, 13429-13434, 2012. (IF: 4.484 )

[14] Qingming Deng, Jun Pan, Xiaohui Yin, Xiaofeng Wang, Lina Zhao*, Seunggu Kang, Camilo A. Jimenez Cruz, Ruhong Zhou, Jingyuan Li*, “Towards High Conductivity, Selectivity and Controllability of Water Desalination with FePc Nanopores”, Phys. Chem. Chem. Phys., 18, 8140-8147, 2016. (IF: 4.493)

[15] Liang Yan, Yanan Chang, Wenyan Yin, Xiaodong Liu, Debao Xiao, Gengmei Xing, Lina Zhao*, Zhanjun Gu*, Yuliang Zhao*, “Biocompatible and flexible graphene oxide/ upconversion nanoparticle hybrid film for optical pH sensing”Phys. Chem. Chem. Phys., 16, 1576-1582, 2014. (IF: 4.493)

[16] Lili Zhao, Qiao Chen, Yamin Zhang, Lina Zhao*, “Current Induced Heat Generation in Ferromagnet-Quantum Dot-Ferromagnet System”, Materials, 8, 3854-3863, 2015. (IF:2.651)

[17] Yawei Zhao, Changling Zou, Hongkang Zhao, Lina Zhao*, “Nanoprobes in Biomedical Detection”, SCI. China. Chem., 59, 255-263, 2016. (IF: 4.448)

[18] Xu Li, Nan Li, Lina Zhao*, “The Reactive Activities of Natural Amino Acids: Key Principles of Peptide-Templated Au Cluster Synthesis”, Sci. Bull., 61, 1732-1738, 2016. (IF: 4.136 )

[19] Lina Zhao, “Chapter14 Molecular Simulation Methods for Bio-effects of Nanomaterials”, Toxicology of Nanomaterials, 2016. (Wiley-VCH出版)


Copyright © 2011, Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety,
Chinese Academy of Sciences