Liming Wang Ph. D.

   Associate Professor
   Key Lab for Biomedical Effects of Nanomaterials and Nanosafety,
   Institute of High Energy Physics, Chinese Academy of Science (CAS).
   19B YuquanLu, Beijing, 100049, China

   Email: wangliming@ihep.ac.cn

 


Research Experience

Sep. 1999 ~ Jul. 2003, Bachelor, School of Life Sciences, Sichuan University
Sep. 2004 ~ Jul. 2007, Master, School of Life Sciences, Sichuan University
Sep. 2007 ~ Jul. 2011, Ph. D., National Center for Nanoscience and Technology of China
Jul. 2011 ~ Nov. 2013, Assistant Professor, Institute of High Energy Physics, CAS
Dec. 2013 ~Present, Associate Professor, Institute of High Energy Physics, CAS

Research Interests

1. Drug efficacy study of nanomedicine

2. Risk assessment of manipulated nanomaterials: Nano-Bio interfacial structures, biological effects, and methods

3. The design of functional nanoplatforms and their biomedical applications

Selected Publications

1.         Wang, L. M.; Lin, X. Y.; Wang, J.; Hu, Z. J.; Ji, Y. L.; Hou, S.; Zhao, Y. L.; Wu, X. C.; Chen, C. Y. Novel Insights into Combating Cancer Chemotherapy Resistance Using a Plasmonic Nanocarrier: Enhancing Drug Sensitiveness and Accumulation Simultaneously with Localized Mild Photothermal Stimulus of Femtosecond Pulsed Laser. Advanced Functional Materials 2014, DOI: 10.1002/adfm.201400015. A front cover paper.

2.         Wang, L. M.; Li, J. Y.; Pan, J.; Jiang, X. M.; Ji, Y. L.; Li, Y. F.; Qu, Y.; Zhao, Y. L.; Wu, X. C.; Chen, C. Y. Revealing the Binding Structure of the Protein Corona on Gold Nanorods Using Synchrotron Radiation-Based Techniques: Understanding the Reduced Damage in Cell Membranes. Journal of the American Chemical Society 2013, 135, 17359.

3.         Wang, L. M.; Jiang, X. M.; Ji, Y. L.; Bai, R.; Zhao, Y. L.; Wu, X. C.; Chen, C. Y. Surface Chemistry of Gold Nanorods: Origin of Cell Membrane Damage and Cytotoxicity. Nanoscale 2013, 5, 8384.

4.         Zhang, L. M.; Wang, L. M.( Equal contribution); Hu, Y. L.; Liu, Z. G.; Tian, Y.; Wu, X. C.; Zhao, Y. L.; Tang, H. R.; Chen, C. Y.; Wang, Y. L. Selective Metabolic Effects of Gold Nanorods on Normal and Cancer Cells and Their Application in Anticancer Drug Screening. Biomaterials 2013, 34, 7117.

5.         Zhang, Z. J.; Wang, L. M.( Equal contribution); Wang, J.; Jiang, X. M.; Li, X. H.; Hu, Z. J.; Ji, Y. L.; Wu, X. C.; Chen, C. Y. Mesoporous Silica-Coated Gold Nanorods a Light-Mediated Multi- functional Theranostic Platform for Cancer Treatment. Advanced Materials 2012, 24, 1418. A cover Paper.                                           

6.         Wang, L. M.; Liu, Y.; Li, W.; Jiang, X. M.; Ji, Y.L.; Wu; X. C.; Xu, L. G.; Qiu, Y.; Zhao K.; Wei, T. T.; Li, Y. F.; Zhao, Y. L.; Chen, C. Y. Selective Targeting of Gold Nanorods at the Mitochondria of Cancer Cells: Implications for Cancer Therapy. Nano Letters 2011, 11, 772.                                                        

7.         Wang, L. M.; Li, Y. F.; Zhou, L. J.; Liu, Y.; Meng, L.; Zhang, K.; Wu, X. C.; Zhang, L. L.; Li, B.; Chen, C. Y. Characterization of Gold Nanorods in vivo by Integrated Analytical Techniques: Their Uptake, Retention and Chemical Forms. Analytical and Bioanalytical Chemistry 2010, 396, 1105.

8.         Ge, C. C.; Du, J. F.; Zhang, L.; Wang, L. M.; Liu, Y.; Li, D. H.; Yang, Y. L.; Zhou, R. H.; Zhao, Y. L.; Chai, Z. F.; Chen, C. Y. Binding of Blood Proteins to Carbon Nanotubes Reduces Cytotoxicity. Proceedings of the National Academy of Sciences 2011, 108, 16968.

9.         Sun, C.J.; Yang, H.; Yuan, Y.; Tian, X.; Wang, L. M.; Guo, Y.; Xu, L.; Lei, J. L.; Gao, N.; Anderson, G.; Liang, X. J.; Chen, C. Y.; Zhao, Y. L.; Nie, G. J. Controlling Assembly of Paired Gold Clusters within Protein Nanoreactor for in vivo Kidney Targeting and Biomedical Imaging. Journal of the American Chemical Society 2011, 133, 8617.