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  • Location: Home > Faculty and Staff
    Juan Li

      Juan Li, Associate Researcher, PhD
      Chinese Academy of Sciences Key Lab for Biomedical Effects of Nanomaterials and
      Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences (CAS). 
      Fax: +86-10-8823-6456



    Dr. Juan Li earned his Ph.D. in Applied Chemistry from Beijing Institute of Technology in 2009. He held post-doctor and faculty at the Institute of High Energy Physics, Chinese Academy of Sciences in Beijing. Dr. Li is exchange scholar visitor in University of California at Los Angeles (UCLA) for nanomedicine research now.

    Research Interests
    (1) The toxicological effects of nanomaterials including identification of nano-hazards using animal, cellular and molecular models by oral administration.

    (2) The surface chemistry of fullerenes, graphic etc. carbon nanoparticles and their novel properties for the purposes of enhancing the biomedical functions or reducing the potential toxicity.

    (3) The biomedical multifunctional nanomaterials for cancer treatment and imaging.

    Recent Publications

    [1] Juan Li, R Lei, X Li, F Xiong, Q Zhang, Y Zhou, S Yang, Y Chang, K Chen, The antihyperlipidemic effects of fullerenol nanoparticles via adjusting the gut microbiota in vivoParticle and Fibre Toxicology, 2018,15 (1), 5

    [2]C Li, H Huang, R Cui, Juan Li, X Guo, H Yao, B Liu, B Xu, Y Li, S Liu, J Dong, Fluorescent activatable gadofullerene nanoprobes as NIR-MR dual-modal in vivo imaging contrast agent, Colloids and Surfaces B: Biointerfaces 2018,171, 159-166

    [3] Juan Li, Shengmei Yang, Jiaqi Yu, Rongli Cui, Ru Liu, Runhong Lei ...Lipid- and Gut Microbiota-modulating Effects of Graphene Oxide Nanoparticles in High-fat Diet-induced Hyperlipidemic Mice. RSC Advances 2018,8, 31366 – 31371

    [4] Juan Li, S Yang, R Cui, Y Chang, W Gu, X Guo, H Huang, K Chen, H Geng, ...The interactions between plasma proteins and fullerols by isothermal titration calorimetry,Nanomedicine: Nanotechnology, Biology and Medicine 2018,14 (5), 1781

    [5] S Yang, F Xiong, K Chen, Y Chang, X Bai, W Yin, W Gu, Q Wang, Juan Li, ...Impact of Titanium Dioxide and Fullerenol Nanoparticles on Caco-2 Gut Epithelial Cells, Journal of nanoscience and nanotechnology 2018,18 (4), 2387-2393

    [6] S Xia, J Li, M Zu, Juan Li, J Liu, X Bai, Y Chang, K Chen, W Gu, L Zeng, ...Small size fullerenol nanoparticles inhibit thrombosis and blood coagulation through inhibiting activities of thrombin and FXa, Nanomedicine: Nanotechnology, Biology and Medicine 2018,14 (3), 929-939

    [7] R Lei, X Bai, Y Chang, Juan Li, Y Qin, K Chen, W Gu, S Xia, J Zhang, Z Wang, ...Effects of Fullerenol Nanoparticles on Rat Oocyte Meiosis Resumption

    International journal of molecular sciences 2018,19 (3), 699

    [8] Juan Li, S Yang, J Yu, R Cui, R Liu, R Lei, Y Chang, H Geng, Y Qin, W Gu,...Lipid-and gut microbiota-modulating effects of graphene oxide nanoparticles in high-fat diet-induced hyperlipidemic mice,RSC Advances 2018,8 (55), 31366-31371

    [9] S Ma, J Zhang, S Xia, W Yin, Y Qin, R Lei, L Mei, Juan Li*, G Xing*...Three-dimensional Angiography Fused with CT/MRI for Multimodal Imaging of Nanoparticles Based on Ba4Yb3F17: Lu3+, Gd3+,Nanoscale,2018

    [10] Juan Li, S Yang, R Lei, W Gu, Y Qin, S Ma, K Chen, Y Chang, X Bai, S Xia, ...Oral administration of rutile and anatase TiO 2 nanoparticles shifts mouse gut microbiota structure,2018,Nanoscale 10 (16), 7736-7745

    [11] W Gu, X Bai, K Ren, X Zhao, S Xia, J Zhang, Y Qin, R Lei, K Chen, Juan Li, Gengmei Xing, Mono-fullerenols modulating cell stiffness by perturbing actin bundling,Nanoscale 10 (4), 1750-1758

    [12] J Yu, W Yin, T Peng, Y Chang, Y Zu, Juan Li, X He, X Ma, Z Gu, Y Zhao, Biodistribution, excretion, and toxicity of polyethyleneimine modified NaYF 4: Yb, Er upconversion nanoparticles in mice via different administration routes, Nanoscale,2017, 9 (13), 4497-4507

    [13] H Geng, YN Chang, X Bai, S Liu, Q Yuan, W Gu, Juan Li, K Chen, G Xing,.. Fullerenol nanoparticles suppress RANKL-induced osteoclastogenesis by inhibiting differentiation and maturation, Nanoscale 2017, 9 (34), 12516-12523

    [14] YN Chang, M Zhang Juan Li, K Chen, W Gu, G Xing,Utilizing a microfluidic device to enrich and fluorescently detect circulating tumor cells,Science Bulletin 2017, 7, 001

    [15] W Yin, L Yan, J Yu, G Tian, L Zhou, X Zheng, X Zhang, Y Yong, Juan Li, Z Gu, High-Throughput Synthesis of Single-Layer MoS2 Nanosheets as a Near-Infrared Photothermal-Triggered Drug Delivery for Effective Cancer Therapy,2014,ACS nano 8 (7), 6922-6933

    [16] K Chen, M Zhang, YN Chang, L Xia, W Gu, Y Qin, Juan Li, S Cui, G Xing, Utilizing gold nanoparticle probes to visually detect DNA methylation,Nanoscale research letters 2016, 11 (1), 304   7

    [17] L Xia, W Gu, M Zhang, YN Chang, K Chen, X Bai, L Yu, Juan Li, S Li, G Xing, Endocytosed nanoparticles hold endosomes and stimulate binucleated cells formation, Particle and fibre toxicology, 2016, 13 (1), 63       7

    [18] F Liu, F Xiong, Y Fan, Juan Li, H Wang, G Xing, F Yan, F Tai, R He, Facile and scalable fabrication engineering of fullerenol nanoparticles by improved alkaline-oxidation approach and its antioxidant potential in maize. Journal of Nanoparticle Research 2016,18 (11), 338  

    [19] F Xiong, Juan Li, H Wang, G Xing, R He, Evaluation of a series of different surface charged fullerenol nanoparticles as reactive oxygen species scavengers and potential cytoprotective agents, Journal of Nanoscience and Nanotechnology 2016,16 (7), 7170-7174

    [20] J Jin, Y Dong, Y Wang, L Xia, W Gu, X Bai, Y Chang, M Zhang, K Chen, Juan Li, Gengmei Xing, ...Fullerenol Nanoparticles with structural activity induce variable intracellular actin filament morphologies, Journal of biomedical nanotechnology 2016,12 (6), 1234-1244

    [21] Juan Li, W Yang, R Cui, D Wang, Y Chang, W Gu, W Yin, X Bai, K Chen, L Xia, ...Metabolizer in vivo of fullerenes and metallofullerenes by positron emission tomography,Nanotechnology, 2016, 27 (15), 155101

    [22] Cheng Li, Rongli Cui, Liangzhu Feng, Juan Li, Huan Huang, Huanli Yao ...Synthesis of a UCNPs@SiO2@gadofullerene nanocomposite and its application in UCL/MR bimodal imaging,RSC Adv.2016, 101, 98968-98974      

    [23] Juan Li, R Cui, Y Chang, X Guo, W Gu, H Huang, K Chen, G Lin, J Dong, ...Adaption of the structure of carbon nanohybrids toward high-relaxivity for a new MRI contrast agent, RSC Advances,2016, 6 (63), 58028-58033

    [24] R Cui, Juan Li, H Huang, M Zhang, X Guo, Y Chang, M Li, J Dong, B Sun, ...Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents. Nano Research 2015,8 (4), 1259-1268 

    Copyright © 2011, Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety,
    Chinese Academy of Sciences