Weiyue Feng----Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety

    Weiyue Feng, Professor, PhD
     Chinese Academy of Sciences Key Lab for Biomedical Effects of Nanomaterials and
     Nanosafety,  Institute of High Energy Physics, Chinese Academy of Sciences (CAS)
    Tel/Fax：010-88233209
     Email: fengwy@ihep.ac.cn
     Mail address: 19B, Yuquan Road, Shijingshan District, Institute of High Energy Physics,
     Chinese Academy of Sciences, Beijing 100049, China

Biography
Graduated from Fudan University of Applied Chemistry in 1989. Got her Ph.D degree in Chemical Science from Graduate School of the Chinese Academy of Sciences in 1998. Her doctoral dissertation obtained “National Outstanding Doctoral Dissertations” award in 2001.

Research Interests
1. Biological/toxic effects of nanomaterials and the association with their physicochemical properties
2. Biological effects of nanomaterials: biological and chemical mechanism exploration;
3. Multiphase chemical reactions of ultrafine aerosols and their healthy evaluation
4. Methods of synchrotron radiation techniques and other nuclear techniques in the biological and environmental detection.
5. Single cell and single particle analysis by ICP-MS

Current research contents
1. To explore how nanomaterials (carbon nanotubes, graphene, gold and silver nanoparticles, etc.) interact with the living systems: the physicochemical properties and the biological responses.
2. Using nanoparticles as models to explore chemical reactions with air pollutants at particle-gas phases and evaluation the health effects.
3. Developing new method to quantitative analysis single cells by ICP-MS.
4. Application of synchrotron radiation techniques in the study of effects of nanomaterials in biological and environmental systems: the micro-distribution in tissues; the chemical statues; the interaction of nanomaterials with biological and environmental medium

Recent Publications
1. Bing Wang, Xiao He, Zhiyong Zhang,* Yuliang Zhao, Weiyue Feng*, Nanomaterials in vivo: Blood Circulation and Organ Clearance. Acc. Chem. Res. 2013, 46(3): 761-769.

2. Wang, Meng; Zheng, Ling-Na; Wang, Bing; Chen, Hanqing; Zhao, Yuliang; Chai, Zhifang; Reid, Helen; Sharp, Barry; Feng, Weiyue*, Quantitative analysis of gold nanoparticles in single cells by laser ablation inductively coupled plasma-mass spectrometry, Anal. Chem. 2014, 86: 10252-10256.

3. Hanqing Chen, Bing Wang, Ruifang Zhao, Di Gao, Ming Guan, Lingna Zheng, Xiaoyan Zhou, Zhifang Chai, Yuliang Zhao, Weiyue Feng*, Co-culture with low-dose SWCNT attenuates bacterial invasion and inflammation in human enterocyte-like Caco-2 cells. Small, 2015, 11: 4366-4378.

4. Hanqing Chen, Bing Wang, Di Gao, Ming Guan, Lingna Zheng, Hong Ouyang, Zhifang Chai, Yuliang Zhao, Weiyue Feng* Broad-Spectrum Antibacterial Activity of Carbon Nanotubes to Human Gut Bacteria. Small 2013, 9(16): 2735-2746.

5. Bing Wang, Xiaoyan Zhou, Dongqi Wang,* Jun-Jie Yin, Hanqing Chen, Xingfa Gao, Jing Zhang, Kurash Ibrahim, Zhifang Chai, Weiyue Feng* and Yuliang Zhao, Structure and Catalytic Activities of Ferrous Center Confined on the Interface between Carbon Nanotube and Humic Acid. Nanoscale, 2015, 7: 2651-2658.

6. Hanqing Chen, Ruifang Zhao, Bing Wang, Lingna Zheng, Hong Ouyang, Hailong Wang, Xiaoyan Zhou, Dan Zhang, Zhifang Chai, Yuliang Zhao, Weiyue Feng*, Acute Oral Administration of Single-Walled Carbon Nanotubes Increases Intestinal Permeability and Inflammatory Responses: Association with the Changes in Gut Microbiota in Mice. Adv. Healthcare Mater. 2018, 7(13):1701313.

7. Xiaoyan Zhou#, Bing Wang#, Tu Lan, Hanqing Chen, Hailong Wang, Ye Tao, Zhihong Li, Kurash Ibrahim, Dongqi Wang*, Weiyue Feng*, Chirality of Graphene Oxide Humic Acid Sandwich Complex Induced by a Twisted, Long-Range-Ordered Nanostructure. J. Phys. Chem. C, 2016, 120: 25789-25795. # Co-first author.

8. Wang Bing, Feng Weiyue,* Chai Zhifang, Zhao Yuliang, Probing the interaction at nano-bio interface using synchrotron radiation-based analytical techniques. Sci. China Chem. 2015, 58: 768-779.

9. Hanqing Chen, Bing Wang, Weiyue Feng*, Wei Du, Hong Ouyang, Zhifang Chai, and Xiaolin Bi*, Oral magnetite nanoparticles disturb the development of Drosophila melanogaster from oogenesis to adult emergence. Nanotoxicology 2015, 9(3): 302-312.

10. Hailong Wang#, Bing Wang#, Meng Wang, Lingna Zheng, Hanqing Chen, Zhifang Chai, Yuliang Zhao, Weiyue Feng*, Time-resolved ICP-MS Analysis of Mineral Element Contents and Distribution Patterns in Single Cells. Analyst, 2014, 140: 523-531. # Co-first author.